ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Neoplasms: Functional Pancreatic Endocrine Tumor Syndromes

2012/01/01 by Robert T. Jensen, Guillaume Cadiot, Maria Luisa Brandi +7 · 4 citations
Medicine · #Neuroendocrine Tumor Research Advances #Pancreatic and Hepatic Oncology Research #Neuroblastoma Research and Treatments

paper · pdf · doi:10.1159/000335591

openalex publication_date 2012/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Abstract

Gastrinomas are neuroendocrine neoplasms, usually located in the duodenum or pancreas, that secrete gastrin and cause a clinical syndrome known as Zollinger-Ellison syndrome (ZES). ZES is characterized by gastric acid hypersecretion resulting in severe peptic disease (peptic ulcer disease (PUD), gastroesophageal reflux disease (GERD)) In this section, ZES due to both duodenal and pancreatic gastrinomas will be covered together because clinically they are similar Specific points related to gastrinomas associated with the genetic syndrome of Multiple Endocrine Neoplasia type 1 (MEN1) (25% of cases) will also be mentioned

Citations

• Insulin secretion and insulin-producing tumors
• ENETS Consensus Guidelines for the Management of Patients with Liver and Other Distant Metastases from Neuroendocrine Neoplasms of Foregut, Midgut, Hindgut, and Unknown Primary

Cited by

• ENETS Consensus Guidelines for the Management of Patients with Liver and Other Distant Metastases from Neuroendocrine Neoplasms of Foregut, Midgut, Hindgut, and Unknown Primary
• Therapy for metastatic pancreatic neuroendocrine tumors.
• Consensus Recommendations for the Diagnosis and Management of Pancreatic Neuroendocrine Tumors: Guidelines from a Canadian National Expert Group
• Pancreatic cancer [wikipedia]