Multimodal Influence of Estrogen upon Gonadotropin-Releasing Hormone Neurons

1998/06/01 by Allan E. Herbison · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · #Hypothalamic control of reproductive hormones #Estrogen and related hormone effects #Growth Hormone and Insulin-like Growth Factors

paper · doi:10.1210/edrv.19.3.0332

openalex publication_date 1998/06/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15

Abstract

I. Introduction II. Effects of Estrogen on GnRH Neurons A. Sexual differentiation B. Biosynthesis of GnRH C. Biosynthesis of galanin D. Electrical activity of GnRH neurons E. GnRH secretion F. GnRH degradation G. Ultrastructural changes involving GnRH neurons H. Summary of estrogen’s influence on GnRH cells III. Brain Sites of Estrogen Influence on GnRH Neurons A. Sites of estrogen’s stimulatory sites B. Sites of estrogen’s inhibitory action C. Summary IV. Pathways for Estrogen Regulation of GnRH Neurons A. Direct regulation of GnRH neurons B. Estrogen-receptive neurons as intermediaries C. Glial cells as intermediaries D. Summary V. Model of Estrogen Action on GnRH Neurons VI. Concluding Remarks

Citations

• Cloning of a novel receptor expressed in rat prostate and ovary.
• Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β
• Comparative distribution of estrogen receptor-? and -? mRNA in the rat central nervous system
• ERβ: Identification and characterization of a novel human estrogen receptor

Cited by

• Pharmacodynamics of estradiol [wikipedia]