2000/01/01 by Meike L. Uhler, Jay W. Marks, Howard L. Judd · 2 citations
Medicine · #Gallbladder and Bile Duct Disorders #Cholangiocarcinoma and Gallbladder Cancer Studies #Bone health and treatments
paper · doi:10.1097/00042192-200007030-00006
openalex publication_date 2000/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30
OBJECTIVE: To examine the role of estrogen replacement therapy on the development of gallbladder disease in postmenopausal women. DESIGN: Systematic review of the English literature was conducted. All studies that addressed the association between hormone replacement therapy and gallbladder disease published from 1970 to the present were reviewed. RESULTS: Seven observational studies, two clinical trials, two case series, and one nonrandomized and three randomized investigations were reviewed. The results of each study were reported and analyzed. CONCLUSIONS: Estrogen replacement therapy in postmenopausal women increased the chances for gallstone formation.