The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties.

1989/07/01 by L. Tora, Làszlò Tora, Alaka Mullick +8 · 4 citations
Biochemistry, Genetics and Molecular Biology · #Estrogen and related hormone effects #Steroid Chemistry and Biochemistry #Viral Infectious Diseases and Gene Expression in Insects

paper · pdf · doi:10.1002/j.1460-2075.1989.tb03604.x

crossref issued 1989/07/01 · crossref published 1989/07/01 · crossref published-online 1989/07/01 · crossref published-print 1989/07/01 · openalex publication_date 1989/07/01 · crossref created 2018/09/06 · openalex created_date 2025/10/10 · crossref deposited 2026/05/19 · crossref indexed 2026/07/09 · openalex updated_date 2026/07/23

Citations

• Genomic organization of the human oestrogen receptor gene.
• Cloning of the human estrogen receptor cDNA.
• Sequence and Expression of Human Estrogen Receptor Complementary DNA
• The Anatomy and Taxonomy of Protein Structure

Cited by

• T:G Mismatch-specific Thymine-DNA Glycosylase Potentiates Transcription of Estrogen-regulated Genes through Direct Interaction with Estrogen Receptor α
• Mutagenesis of cysteines in the hormone binding domain of the human estrogen receptor. Alterations in binding and transcriptional activation by covalently and reversibly attaching ligands
• Human Estrogen Receptor β Binds DNA in a Manner Similar to and Dimerizes with Estrogen Receptor α
• Estrogen receptor alpha [wikipedia]