1996/01/01 by Ingar Palmlund · 3 citations
Environmental Science · Biochemistry, Genetics and Molecular Biology · #Effects and risks of endocrine disrupting chemicals #Carcinogens and Genotoxicity Assessment #Toxic Organic Pollutants Impact
paper · doi:10.3109/01674829609025667
openalex publication_date 1996/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15
The experiences of diethylstilbestrol (DES), used as a medication for pregnant women, provide a panorama of the effects of an elevated exposure to xenoestrogens during the development of a fetus. DES was common as pregnancy medication in North America, and several European countries from the 1950s into the 1970s. It may still be prescribed as pregnancy medication in Third World countries. DES exposure in utero has been shown to have carcinogenic, teratogenic and reproductive effects. The medical community needs to be alerted to appropriate treatment of patients exposed in utero to elevated levels of estrogens.