2012/10/08 by Deborah Matthews, Tim Cheetham · 2 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Sexual Differentiation and Disorders #Hormonal and reproductive studies #Growth Hormone and Insulin-like Growth Factors
paper · doi:10.1111/cen.12065
openalex publication_date 2012/10/08 · openalex created_date 2016/06/24 · openalex updated_date 2026/05/21
Patients with Congenital adrenal hyperplasia due to partial deficiency in the enzyme 21-hydroxylase can present in childhood or adolescence with signs of adrenal androgen excess. Strategies to reduce the impact of androgen excess in females include cosmetic measures as well as antiandrogens and agents such as the combined oral contraceptive pill. Glucocorticoid may not be appropriate straightaway but can be introduced if other measures are ineffective or when pregnancy is planned.