2008/10/01 by Jared J. Grantham · 543 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Abdominal pain #Autosomal dominant polycystic kidney disease #Creatinine #Cyst #Flank pain #Genetic and Kidney Cyst Diseases #Gross hematuria #Internal medicine #Kidney #Medicine #Polycystic kidney disease #Renal and related cancers #Renal cell carcinoma treatment #Surgery #Urology
paper · doi:10.1056/nejmcp0804458
published in New England Journal of Medicine 359(14), 1477-1485 (Massachusetts Medical Society)
openalex publication_date 2008/10/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/28
Shortly after being elbowed in the flank during a basketball game, a 35-year-old healthy man has severe, colicky abdominal pain followed by gross hematuria. A renal ultrasound scan reveals bilateral polycystic kidneys and liver cysts. The blood pressure is 160/100 mm Hg. The serum creatinine concentration is 0.9 mg per deciliter (80 μmol per liter). The pain subsides in 2 days with analgesics, rest, and fluids; the gross hematuria resolves in 4 days, although microscopic hematuria persists.