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Inactivation of Transmissible Spongiform Encephalopathy (Prion) Agents by Environ LpH

2004/01/27 by Richard Race, Gregory J. Raymond · 1 citation
Biochemistry, Genetics and Molecular Biology · #Prion Diseases and Protein Misfolding

paper · doi:10.1128/jvi.78.4.2164-2165.2004

openalex publication_date 2004/01/27 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22

Abstract

Agents causing transmissible spongiform encephalopathy (TSE) diseases are resistant to inactivation by several conventional decontamination methods. Using an animal bioassay, we compared the TSE agent disinfectant efficacy of a commercially available product referred to alternatively as LpH-SE, LpH-AG, or LpH-st to that of a similarly named but differently formulated product, Environ LpH, which was found to be an effective TSE agent disinfectant in a previous study. Here, we found LpH-SE to be at least 10(4)-fold to 10(5)-fold less effective than Environ LpH.

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