2012/02/01 by David L. Larson, Sharon E. Jacob, Christen M. Mowad · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · #Contact Dermatitis and Allergies #Nail Diseases and Treatments #Plant Reproductive Biology
paper · doi:10.1097/der.0b013e31823e202d
openalex publication_date 2012/02/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/25
Tea tree oil is an increasingly popular ingredient in a variety of household and cosmetic products, including shampoos, massage oils, skin and nail creams, and laundry detergents. Known for its potential antiseptic properties, it has been shown to be active against a variety of bacteria, fungi, viruses, and mites. The oil is extracted from the leaves of the tea tree via steam distillation. This essential oil possesses a sharp camphoraceous odor followed by a menthol-like cooling sensation. Most commonly an ingredient in topical products, it is used at a concentration of 5% to 10%. Even at this concentration, it has been reported to induce contact sensitization and allergic contact dermatitis reactions. In 1999, tea tree oil was added to the North American Contact Dermatitis Group screening panel. The latest prevalence rates suggest that 1.4% of patients referred for patch testing had a positive reaction to tea tree oil.