Animal Experiments in Biomedical Research: A Historical Perspective

2013/03/19 by Nuno Henrique Franco · 2 citations
Veterinary · #Animal testing and alternatives

paper · pdf · doi:10.3390/ani3010238

openalex publication_date 2013/03/19 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22

Abstract

The use of non-human animals in biomedical research has given important contributions to the medical progress achieved in our day, but it has also been a cause of heated public, scientific and philosophical discussion for hundreds of years. This review, with a mainly European outlook, addresses the history of animal use in biomedical research, some of its main protagonists and antagonists, and its effect on society from Antiquity to the present day, while providing a historical context with which to understand how we have arrived at the current paradigm regarding the ethical treatment of animals in research.

Citations

• The Principles of Humane Experimental Technique
• The life and works of Louis Pasteur
• The Contributions of Paul Ehrlich to Pharmacology: A Tribute on the Occasion of the Centenary of His Nobel Prize
• Ideals of Science and Their Discontents in Late Nineteenth-Century American Medicine
• Integration and Stable Germ Line Transmission of Genes Injected into Mouse Pronuclei
• Claude Bernard and the Constancy of the Internal Environment
• "A Time to Heal": The Diffusion of Listerism in Victorian Britain
• Oxford Handbook of Animal Ethics.

Cited by

• Alcmaeon of Croton [wikipedia]
• Domestic rabbit [wikipedia]