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The Neuron Doctrine, Redux

2005/11/03 by Theodore H. Bullock, Michael V. L. Bennett, Daniel Johnston +3 · 2 citations
Neuroscience · #Neuroscience and Neuropharmacology Research #Neural dynamics and brain function #Photoreceptor and optogenetics research

paper · doi:10.1126/science.1114394

openalex publication_date 2005/11/03 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/23

Abstract

In their Perspective, [ Bullock et al. ][1] discuss recent evidence suggesting that the Neuron Doctrine, conceived nearly a century ago, cannot encompass important aspects of information processing in the brain. Intercellular communication by gap junctions, slow electrical potentials, action potentials initiated in dendrites, neuromodulatory effects, extrasynaptic release of neurotransmitters, and information flow between neurons and glia all contribute to information processing. Revisiting the Neuron Doctrine suggests that future research outside its limits may lead to new insights into the unique capabilities of the human brain. [1]: http://www.sciencemag.org/cgi/content/full/310/5749/791

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