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Malpighi and the Discovery of Capillaries

2007/01/01 by John Pearce · 3 citations
Neuroscience · Arts and Humanities · #Neurology and Historical Studies #History of Medicine Studies

paper · pdf · doi:10.1159/000107974

openalex publication_date 2007/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/05/22

Abstract

Leonardo da Vinci clearly observed and described capillaries. Using the microscope, Marcello Malpighi examined the brain and major organs to demonstrate their finer anatomical features. This led to his discovery in 1661, of capillaries that proved fundamental to our understanding of the vascular system in the brain and cord. He hypothesized that capillaries were the connection between arteries and veins that allowed blood to flow back to the heart in the circulation of the blood, as first asserted by William Harvey.

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