1911/04/01 by Peyton Rous · 6 citations
Medicine · #Sarcoma Diagnosis and Treatment
paper · pdf · doi:10.1084/jem.13.4.397
openalex publication_date 1911/04/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29
A transmissible sarcoma of the chicken has been under observation in this laboratory for the past fourteen months, 1 and it has assumed of late a special interest because of its extreme malignancy and a tendency to wide-spread metastasis3 In a careful study of the growth, tests have been made to determine whether it can be transmitted by a filtrate free of the tumor cells.Attempts to so transmit rat, mouse, and dog tumors have never succeeded; and it was supposed that the sarcoma of the fowl would not differ from them in this regard, since it is a typical neoplasm.On the contrary, small quantities of a cell-free filtrate have sufficed to transmit the growth to susceptible fowls.EXPERIMENTS.