Lab-chip HPLC with integrated droplet-based microfluidics for separation and high frequency compartmentalisation

2012/01/01 by Jinyoung Kim, Soongwon Cho, Dong‐Ku Kang +4 · 3 citations
Engineering · #Microfluidic and Capillary Electrophoresis Applications #Innovative Microfluidic and Catalytic Techniques Innovation #Electrowetting and Microfluidic Technologies

paper · doi:10.1039/c2cc33774f

openalex publication_date 2012/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22

Abstract

We demonstrate the integration of a droplet-based microfluidic device with high performance liquid chromatography (HPLC) in a monolithic format. Sequential operations of separation, compartmentalisation and concentration counter were conducted on a monolithic chip. This describes the use of droplet-based microfluidics for the preservation of chromatographic separations, and its potential application as a high frequency fraction collector.

Citations

• Control and detection of chemical reactions in microfluidic systems
• The origins and the future of microfluidics

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• Seamless Combination of High-Pressure Chip-HPLC and Droplet Microfluidics on an Integrated Microfluidic Glass Chip
• Microfluidics [wikipedia]