2008/12/22 by Venkatachalam Chokkalingam, Stephan Herminghaus, Ralf Seemann · 3 citations
Engineering · #Innovative Microfluidic and Catalytic Techniques Innovation #Electrowetting and Microfluidic Technologies #Microfluidic and Capillary Electrophoresis Applications
paper · doi:10.1063/1.3050461
openalex publication_date 2008/12/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/11
The in situ generation of pairs of droplets with excellent monodispersity is essential for quantitative (bio-)chemical reactions in a droplet based microfluidic chip. In the present paper, we demonstrate the simultaneous self-synchronized production of droplets with two different contents by step emulsification. The synchronization is achieved by a pressure cross talk of two connected production units while retaining all relevant properties of a single-step-emulsification unit. Pairs and triplets of droplets can be achieved. While the drop volumes of the two droplet types may be different up to a factor of 2, the excellent monodispersity of each type is retained.