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A Functional Biological Marker is Needed for Diagnosing Magnesium Deficiency

2004/12/01 by Kay B. Franz · 2 citations
Nursing · Medicine · Agricultural and Biological Sciences · #Magnesium in Health and Disease #Parathyroid Disorders and Treatments #Plant Micronutrient Interactions and Effects

paper · doi:10.1080/07315724.2004.10719418

openalex publication_date 2004/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15

Abstract

Functional biological markers or biomarkers are now available for many nutrients which are used as nutritional status markers. Most sources of these biomarkers are products or precursors of enzymatic processes that can be measured in serum and plasma. At this time measurements of total or ionized magnesium (Mg) in serum, plasma, cellular components, urine or Mg retention from a load test are performed, but they may not always reflect Mg nutritional status. Biomarkers for Mg are needed which would reflect changes in biochemical processes where Mg is involved. Biomarkers for Mg need to be identified and evaluated in both animals and humans, with a determination of possible factors that may affect the reaction and biomarker concentrations. Some possible biomarkers for Mg include the following: Na/K ATPase, thromboxane B2, C-reactive protein, and endothelin-1. Other possible biomarkers for Mg need to be identified.

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