2012/11/30 by D. Gamermann, Gamermann, D., Arnau Montagud +7
Biochemistry, Genetics and Molecular Biology · #Bioinformatics and Genomic Networks #FOS: Biological sciences #Genomics and Phylogenetic Studies #Microbial Metabolic Engineering and Bioproduction #Molecular Networks (q-bio.MN)
paper · doi:10.48550/arxiv.1211.7192
openalex publication_date 2012/11/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
A wide range of applications and research has been done with genome-scale metabolic models. In this work we describe a methodology for comparing metabolic networks constructed from genome-scale metabolic models and how to apply this comparison in order to infer evolutionary distances between different organisms. Our methodology allows a quantification of the metabolic differences between different species from a broad range of families and even kingdoms. This quantification is then applied in order to reconstruct phylogenetic trees for sets of various organisms.