2012/06/07 by Marco Goeijenbier, Jiri F. P. Wagenaar, Marga G. A. Goris +7 · 1 citation
Medicine · Immunology and Microbiology · #Viral Infections and Vectors #Viral Infections and Outbreaks Research #Leptospirosis research and findings
paper · doi:10.3109/1040841x.2012.686481
openalex publication_date 2012/06/07 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01
This review presents an overview of the most important rodent-borne hemorrhagic fever pathogens directly transmitted from rodents to humans, namely Leptospira and hantaviruses, together with the New- and Old-World arenaviruses. These zoonotic diseases frequently share clinical symptoms, transmission routes and other epidemiological features and often have an emerging pattern. Differential diagnostics could benefit from a syndrome-based approach grouping these pathogens. In this review extensive descriptions of the epidemiology, clinical symptoms, diagnostics and treatment are provided including a practical overview, listing clinical features, diagnostics and risk factors for each selected rodent-borne hemorrhagic fever pathogen.