The rate at which asexual populations cross fitness valleys

2009/03/14 by Daniel B. Weissman, Michael M. Desai, Daniel S. Fisher +1 · 4 citations
Biochemistry, Genetics and Molecular Biology · Social Sciences · #Evolution and Genetic Dynamics #Evolutionary Game Theory and Cooperation #Genetic diversity and population structure

paper · doi:10.1016/j.tpb.2009.02.006

openalex publication_date 2009/03/14 · crossref created 2009/03/14 · crossref issued 2009/06/01 · crossref published 2009/06/01 · crossref published-print 2009/06/01 · crossref deposited 2021/10/03 · openalex created_date 2025/10/10 · crossref indexed 2026/07/07 · openalex updated_date 2026/08/01

Citations

• Compensatory Mutations, Antibiotic Resistance and the Population Genetics of Adaptive Evolution in Bacteria
• On the Generalized "Birth-and-Death" Process
• PATHOGEN POPULATION GENETICS, EVOLUTIONARY POTENTIAL, AND DURABLE RESISTANCE
• Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli

Cited by

• The Rate of Fitness-Valley Crossing in Sexual Populations
• Cryptic genetic variation can make “irreducible complexity” a common mode of adaptation in sexual populations
• Experiments on the role of deleterious mutations as stepping stones in adaptive evolution
• Irreducible complexity [wikipedia]