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Random auditory stimulation during sleep disturbs traveling slow waves and declarative memory

2026/06/25 by Nora M. Roüast, Deniz Kumral, Steffen Gais +1 · 1 voice
Neuroscience · Psychology · #Sleep and Wakefulness Research #EEG and Brain-Computer Interfaces #Sleep and Work-Related Fatigue

paper · doi:10.1016/j.isci.2026.116601

Abstract

Sleep plays a crucial role in memory consolidation, and various methods have attempted to enhance this process by using auditory stimulation. However, the broader impact of auditory stimulation on sleep physiology and memory retention is not fully understood. Here, we apply random or sham auditory stimulation during an afternoon nap to investigate its effects on neural activity and memory consolidation. Stimulation led to a specific reduction in slow-wave sleep, a decreased slow-wave count, and impaired declarative recall that correlated with the diminished sleep depth. Furthermore, we observed altered slow-wave traveling dynamics, with stimulation resulting in shorter traveling trajectories with less reach and reduced spatial spread, particularly impacting frontal regions. Disruptions in these features further predicted memory deficits. Our findings highlight the role of dynamic slow-wave properties in declarative memory consolidation and reveal some methodological limitations for using auditory cues during sleep, since they may disrupt complex processing patterns.

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