Repurposing haemoproteins for asymmetric metal-catalysed H atom transfer

2025/07/30 by Xiang Zhang, Dongping Chen, María Álvarez +1 · 1 voice · 4 citations
Chemistry · Biochemistry, Genetics and Molecular Biology · #Synthesis and Catalytic Reactions #Adenosine and Purinergic Signaling #Metal-Catalyzed Oxygenation Mechanisms

paper · doi:10.1038/s41586-025-09308-0

Cited by

• Asymmetric Hydrogen Atom Transfer. [europepmc]
• Enzymatic Metal-Hydrogen Atom Transfer with a Cobalt Protoporphyrin Cofactor. [europepmc]
• Asymmetric Reduction of Unactivated Alkenes. [europepmc]
• Challenging the dry core paradigm: hydrated reactivity emerges within micellar cores. [europepmc]

Discussions

• Fantastic work by the Ward lab to repurpose cytochrome #P450 enzymes for a new-to-nature asymmetric metal-catalysed H atom transfer! Just released @Nature : doi.org/10.1038/s415.... A must read!🧪 [bsky, 18 points, 2 comments]