2019/11/14 by David R. Meldrum, Marge A. Morris, Joseph C. Gambone +1 · 1 citation
Medicine · #Sexual function and dysfunction studies #Hormonal and reproductive studies #Urinary Bladder and Prostate Research
paper · doi:10.1080/13685538.2019.1686756
openalex publication_date 2019/11/14 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29
The authors review and discuss numerous factors that influence erectile function and their interactions, based on the published literature. Of critical importance are vascular nitric oxide; nutrition; exercise; weight control and maintaining insulin sensitivity; early treatment of hypertension with attention to effects on erectile function; avoiding sources of oxidative stress such as obesity and smoking; reducing inflammation (e.g. from gingivitis); improving pelvic floor muscle strength; and inhibiting cyclic GMP break-down. The described interventions act on different aspects of erectile biochemistry and physiology. Therefore, combining multiple therapeutic approaches will yield maximum benefits for erectile and vascular and general health.