The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4

2001/12/17 by Assen Roguev, Daniel Schaft, Anna Shevchenko +7 · 9 citations
Biochemistry, Genetics and Molecular Biology · #Fungal and yeast genetics research #Genomics and Chromatin Dynamics #Polyamine Metabolism and Applications

paper · pdf · doi:10.1093/emboj/20.24.7137

crossref issued 2001/12/17 · crossref published 2001/12/17 · crossref published-online 2001/12/17 · crossref published-print 2001/12/17 · openalex publication_date 2001/12/17 · crossref created 2002/07/26 · openalex created_date 2025/10/10 · crossref deposited 2026/05/20 · crossref indexed 2026/06/12 · openalex updated_date 2026/07/23

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• Association of the Histone Methyltransferase Set2 with RNA Polymerase II Plays a Role in Transcription Elongation
• H3 Lysine 4 Is Acetylated at Active Gene Promoters and Is Regulated by H3 Lysine 4 Methylation
• Targeted Recruitment of Set1 Histone Methylase by Elongating Pol II Provides a Localized Mark and Memory of Recent Transcriptional Activity
• Histone H3 Methylation by Set2 Directs Deacetylation of Coding Regions by Rpd3S to Suppress Spurious Intragenic Transcription
• Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast
• COMPASS, a Histone H3 (Lysine 4) Methyltransferase Required for Telomeric Silencing of Gene Expression
• The Paf1 Complex Is Required for Histone H3 Methylation by COMPASS and Dot1p: Linking Transcriptional Elongation to Histone Methylation
• The Bur1/Bur2 Complex Is Required for Histone H2B Monoubiquitination by Rad6/Bre1 and Histone Methylation by COMPASS
• Histone [wikipedia]