The structural basis for agonist and partial agonist action on a β1-adrenergic receptor

2011/01/01 by Tony Warne, Rouslan Moukhametzianov, R. Moukhametzianov +6 · 3 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Neuroscience · #Neuropeptides and Animal Physiology #Pharmacological Effects and Assays #Receptor Mechanisms and Signaling

paper · doi:10.1038/nature09746

crossref issued 2011/01/01 · crossref published 2011/01/01 · crossref published-print 2011/01/01 · openalex publication_date 2011/01/01 · crossref created 2011/01/11 · crossref published-online 2011/01/12 · crossref deposited 2025/03/01 · openalex created_date 2025/10/10 · crossref indexed 2026/08/03 · openalex updated_date 2026/08/04

Citations

• Crystal structure of the human β2 adrenergic G-protein-coupled receptor
• Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
• High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
• Phasercrystallographic software

Cited by

• Structure of an Agonist-Bound Human A 2A Adenosine Receptor
• Differential Modulation of Beta-Adrenergic Receptor Signaling by Trace Amine-Associated Receptor 1 Agonists
• G protein-coupled receptor [wikipedia]