1990/08/10 by Alan Hall · 2 citations
Biochemistry, Genetics and Molecular Biology · #Cellular transport and secretion #Protein Kinase Regulation and GTPase Signaling #Biochemical and Molecular Research
paper · doi:10.1126/science.2116664
openalex publication_date 1990/08/10 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
A substantial number of novel guanine nucleotide binding regulatory proteins have been identified over the last few years but the function of many of them is largely unknown. This article will discuss a particular family of these proteins, structurally related to the Ras oncoprotein. Approximately 30 Ras-related small guanosine triphosphate (GTP)-binding proteins are known, and from yeast to man they appear to be involved in controlling a diverse set of essential cellular functions including growth, differentiation, cytoskeletal organization, and intracellular vesicle transport and secretion.