Mobile Elements: Drivers of Genome Evolution

2004/03/11 by Haig H. Kazazian · 6 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Chromosomal and Genetic Variations #Genomics and Phylogenetic Studies #RNA and protein synthesis mechanisms

paper · doi:10.1126/science.1089670

openalex publication_date 2004/03/11 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/04

Abstract

Mobile elements within genomes have driven genome evolution in diverse ways. Particularly in plants and mammals, retrotransposons have accumulated to constitute a large fraction of the genome and have shaped both genes and the entire genome. Although the host can often control their numbers, massive expansions of retrotransposons have been tolerated during evolution. Now mobile elements are becoming useful tools for learning more about genome evolution and gene function.

Citations

• Biology of Mammalian L1 Retrotransposons
• Initial sequencing and analysis of the human genome

Cited by

• Risks from GMOs due to Horizontal Gene Transfer
• Evolution of RNA- and DNA-guided antivirus defense systems in prokaryotes and eukaryotes: common ancestry vs convergence
• Retroposon analysis and recent geological data suggest near-simultaneous divergence of the three superorders of mammals
• Genetic Resources, Genome Mapping and Evolutionary Genomics of the Pig (Sus scrofa)
• The Sinbad retrotransposon from the genome of the human blood fluke, Schistosoma mansoni, and the distribution of related Pao-like elements
• Genome [wikipedia]