Annotation of immune genes in the extinct thylacine (Thylacinus cynocephalus)

2021/02/05 by Emma Peel, Stephen Frankenberg, Carolyn J. Hogg +3 · 1 voice · 7 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Earth and Planetary Sciences · #Bat Biology and Ecology Studies #Biology #Evolution and Paleontology Studies #Evolutionary biology #Gene #Genetics #Genome #Genomics and Phylogenetic Studies #Immune system #Major histocompatibility complex

paper · open access · doi:10.1007/s00251-020-01197-z

published in Immunogenetics 73(3), 263-275 (Springer Science+Business Media)

openalex publication_date 2021/02/05 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Citations

• Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle
• Genome of the Tasmanian tiger provides insights into the evolution and demography of an extinct marsupial carnivore

Cited by

• A Chromosome-Scale Hybrid Genome Assembly of the Extinct Tasmanian Tiger (Thylacinus cynocephalus). [europepmc]
• Emerging trends in genome editing of wild animals. [europepmc]

Discussions

• Ancient DNA can give us insight into the immune system to understand how well a species tolerated disease and and its impact on extinction. Peel et al found the thylacine immune repertoire was typical [bsky, 18 points, 0 comments]