2011/03/21 by Gianvincenzo Zuccotti, Valentina Fabiano · 58 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Alcohol #Ethanol #Excipient #Intensive care medicine #Medicine #Metabolism and Genetic Disorders #Neonatal Health and Biochemistry #Pharmacology #Prenatal Substance Exposure Effects
paper · doi:10.1517/14740338.2011.565328
published in Expert Opinion on Drug Safety 10(4), 499-502 (Taylor & Francis)
openalex publication_date 2011/03/21 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29
Ethanol is commonly used as an excipient in the manufacture of medicines, including the ones intended for administration in children. However, ethanol cannot be considered an inert substance; on the contrary, its use in pharmaceutical preparations is associated with safety issues. Newborns, infants and children are not able to metabolize ethanol as efficiently as adults; as a consequence, they may be at higher risk of both acute and chronic alcohol-related toxicities.