Why genes in pieces?

1978/02/01 by Walter Gilbert · 17 citations
Biochemistry, Genetics and Molecular Biology · Decision Sciences · #Genetics, Bioinformatics, and Biomedical Research #Interdisciplinary Research and Collaboration

paper · pdf · doi:10.1038/271501a0

crossref issued 1978/02/01 · crossref published 1978/02/01 · crossref published-online 1978/02/01 · openalex publication_date 1978/02/01 · crossref published-print 1978/02/09 · crossref created 2005/08/02 · crossref deposited 2025/04/04 · openalex created_date 2025/10/10 · crossref indexed 2026/07/21 · openalex updated_date 2026/07/29

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• A brief history of hemoglobins: plant, animal, protist, and bacteria.
• Evolution of Hemoglobin and Its Genes
• The biology of intron gain and loss
• Origins and Evolution of Spliceosomal Introns
• The Emergence of a Synthetic Theory of Intron Evolution
• Origin and evolution of spliceosomal introns
• Stochastic noise in splicing machinery
• Self-splicing introns in tRNA genes of widely divergent bacteria
• The evolution of spliceosomal introns: patterns, puzzles and progress
• Widespread alternative and aberrant splicing revealed by lariat sequencing
• Can We Measure Memes?
• Introns: The Functional Benefits of Introns in Genomes
• Glutamatergic Model Psychoses: Prediction Error, Learning, and Inference
• Evolution in the light of developmental and cell biology, and vice versa
• Exon [wikipedia]
• Intron [wikipedia]