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Down syndrome as a model of DNA polymerase beta haploinsufficiency and accelerated aging

2011/10/16 by David Patterson, Diane C. Cabelof · 48 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Base excision repair #Biology #DNA #DNA Repair Mechanisms #DNA damage #DNA repair #Down syndrome #Endocrinology #Frailty in Older Adults #Gene #Genetics #Genetics and Neurodevelopmental Disorders #Genome instability #Haploinsufficiency #Oxidative stress #Phenotype #Premature aging #Progeria #Werner syndrome

paper · doi:10.1016/j.mad.2011.10.001

published in Mechanisms of Ageing and Development 133(4), 133-137 (Elsevier BV)

openalex publication_date 2011/10/16 · crossref created 2011/10/16 · crossref issued 2012/04/01 · crossref published 2012/04/01 · crossref published-print 2012/04/01 · crossref deposited 2019/06/17 · openalex created_date 2025/10/10 · crossref indexed 2026/07/07 · openalex updated_date 2026/07/29

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