2017/05/23 by Wolfgang Kreis · 1 citation
Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · Nursing · #Plant biochemistry and biosynthesis #Phytochemistry and Biological Activities #Microbial Metabolites in Food Biotechnology
paper · pdf · doi:10.1055/s-0043-111240
openalex publication_date 2017/05/23 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/04
Abstract This review provides a renewed look at the genus Digitalis. Emphasis will be put on those issues that attracted the most attention or even went through paradigmatic changes since the turn of the millennium. PubMed and Google Scholar were used (“Digitalis” and “Foxglove” were the key words) to identify research from 2000 till 2017 containing data relevant enough to be presented here. Intriguing new results emerged from studies related to the phylogeny and taxonomy of the genus as well as to the biosynthesis and potential medicinal uses of the key active compounds, the cardiac glycosides. Several Eastern and Western Foxgloves were studied with respect to their propagation in vitro. In this context, molecular biology tools were applied and phytochemical analyses were conducted. Structure elucidation and analytical methods, which have experienced less exciting progress, will not be considered here in great detail.