2003/02/14 by Takahito Sugimoto · 2 citations
Medicine · #Electrolyte and hormonal disorders #Bipolar Disorder and Treatment #Restless Legs Syndrome Research
paper · pdf · doi:10.1136/jnnp.74.3.353
openalex publication_date 2003/02/14 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/30
A 31-year-old man was admitted to hospital with of anorexia, binge eating, and self induced vomiting. On admission, he showed a pronounced low weight and disturbance of the body image and was diagnosed as having anorexia nervosa. In addition, electrolyte abnormalities, mainly hypokalaemia, and increased serum renin and aldosterone concentrations were recorded, suggesting pseudo-Bartter syndrome as a complication. Under frequent monitoring of the serum potassium and sodium concentrations, serum electrolytes were gradually corrected, but brain magnetic resonance imaging revealed reversible central pontine myelinolysis (CPM). Although attention has been mainly paid to the association of CPM with rapid correction of hyponatraemia and abnormal osmolality, this case report strongly suggested the involvement of hypokalaemia in the pathogenesis of CPM.