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Extraction, isolation, structure elucidation and evaluation of toxicity, anti-inflammatory and analgesic activity of Pituranthos scoparius constituents

2021/01/01 by Karbab Ahlem, Ahlem, Karbab
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Biological Physics (physics.bio-ph) #FOS: Biological sciences #FOS: Physical sciences #Other Quantitative Biology (q-bio.OT) #physics.bio-ph #q-bio.OT

paper · pdf · doi:10.48550/arxiv.2101.01548

arxiv created 2021/01/01 · arxiv updated 2021/01/06

Abstract

The present work aimed to investigate an ethnobotanical survey about Pituranthos scoparius and assess the toxicity, anti-inflammatory (in vitro, and in vivo) potential, in vitro antioxidant, and analgesic effects of stems and roots of Pituranthos scoparius. Furthermore; to isolate and elucidate the chemical constituents of the n-butanol stem extract of P. scoparius (ButE) and determine the toxicity and anti-inflammatory effects of these compounds added to the ButE. Data from an ethnopharmacological study showed that 24.47 % of people used this plant in folk medicine. Four compounds were isolated from ButE. These compounds were characterized by means of NMR and high-resolution mass spectral (HRMS) data.

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