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Concise review of mechanisms of bacterial adhesion to biomaterial surfaces

1998/01/01 by Yuehuei H. An, Richard J. Friedman · 28 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Bacterial biofilms and quorum sensing #Antimicrobial Peptides and Activities #Biochemical and Structural Characterization

paper · doi:10.1002/(sici)1097-4636(199823)43:3<338::aid-jbm16>3.0.co;2-b

Abstract

This article reviews the mechanisms of bacterial adhesion to biomaterial surfaces and the factors affecting the adhesion. The process of bacterial adhesion includes an initial physicochemical interaction phase (phase one) and a late molecular and cellular interaction phase (phase two), which is a complicated process affected by many factors, including the characteristics of the bacteria themselves, the target material surface, and the environmental factors, such as the presence of serum proteins or bactericidal substances.

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