A Microfluidic System for Controlling Reaction Networks in Time

2003/02/17 by Helen Song, Joshua D. Tice, Rustem F. Ismagilov · 9 citations
Engineering · #Innovative Microfluidic and Catalytic Techniques Innovation #Microfluidic and Capillary Electrophoresis Applications #Electrowetting and Microfluidic Technologies

paper · pdf · doi:10.1002/anie.200390203

openalex publication_date 2003/02/17 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Abstract

Millisecond mixing and transport with no dispersion are achieved by unsteady flows induced in droplets of about 60 pL that travel through winding microfluidic channels (top). Fluorescence can be used to monitor mixing (bottom) or measure reaction rates. In principle, arbitrarily complex reaction networks can be created by combining and splitting streams of such droplets.

Citations

• Transport phenomena

Cited by

• Droplet microfluidics
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• Control and detection of chemical reactions in microfluidic systems
• Droplet based microfluidics
• Microfluidics: Fluid physics at the nanoliter scale
• Microdroplets in Microfluidics: An Evolving Platform for Discoveries in Chemistry and Biology
• Miniaturising the laboratory in emulsion droplets
• Chromatography [wikipedia]