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The cell biology of open and closed mitosis

2013/04/15 by Barbara Boettcher, Yves Barral · 1 citation
Biochemistry, Genetics and Molecular Biology · #Biology #Cell #Cell biology #Cell division #Chromosome #Division (mathematics) #Gene #Genetics #Microtubule and mitosis dynamics #Mitosis #Nuclear Structure and Function #RNA Research and Splicing #Sister chromatids

paper · pdf · doi:10.4161/nucl.24676

openalex publication_date 2013/04/15 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Mitosis is the process of one cell dividing into two daughters, such that each inherits a single and complete copy of the genome of their mother. This is achieved through the equal segregation of the sister chromatids between the daughter cells. However, beyond this simple principle, the partitioning of other cellular components between daughter cells appears to follow a large variety of patterns. We discuss here how the organization of the nuclear envelope during mitosis influences cell division and, subsequently, cellular identity.

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