2014/06/02 by Lise Bergman Nordgren, Erik Hedman‐Lagerlöf, Julie Etienne +6 · 2 citations
Psychology · #Digital Mental Health Interventions #Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes #Mental Health Treatment and Access
paper · pdf · doi:10.1016/j.brat.2014.05.007
openalex publication_date 2014/06/02 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/02
UNLABELLED: A significant proportion of the general population suffers from anxiety disorders, often with comorbid psychiatric conditions. Internet-delivered cognitive behavior therapy (ICBT) has been found to be a potent treatment for patients with specific psychiatric conditions. The aim of this trial was to investigate the effectiveness and cost-effectiveness of ICBT when tailoring the treatment to address comorbidities and preferences for primary-care patients with a principal anxiety disorder. One hundred participants were recruited through their primary-care contact and randomized to either treatment or an active control group. The treatment consisted of 7-10 weekly individually assigned modules guided by online therapists. At post-treatment, 46% of the treatment group had achieved clinically significant improvement on the primary outcome measure (CORE-OM) and between-group effect sizes ranged from d = 0.20 to 0.86, with a mean effect of d = 0.59. At one-year follow-up, within-group effect sizes varied between d = 0.53 to 1.00. Cost analysis showed significant reduction of total costs for the ICBT group, the results were maintained at one-year follow-up and the incremental cost-effectiveness ratio favored ICBT compared to control group. Individually tailored ICBT is an effective and cost-effective treatment for primary-care patients with anxiety disorders with or without comorbidities. TRIAL REGISTRATION: Clinicaltrials.gov: NCT01390168.