1997/06/01 by Maura Ricketts, Neil R. Cashman, E Stratton +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · Business, Management and Accounting · #Prion Diseases and Protein Misfolding #Blood donation and transfusion practices
paper · doi:10.3201/eid0302.970208
openalex publication_date 1997/06/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15
Creutzfeldt-Jakob disease (CJD) has been considered infectious since the mid-1960s, but its transmissibility through the transfusion of blood or blood products is controversial. The causative agent's novel undefined nature and resistance to standard decontamination, the absence of a screening test, and the recognition that even rare cases of transmission may be unacceptable have led to the revision of policies and procedures worldwide affecting all facets of blood product manufacturing from blood collection to transfusion. We reviewed current evidence that CJD is transmitted through blood.