Dissecting the Molecular Pathway Involved in PLK2 Kinase-mediated α-Synuclein-selective Autophagic Degradation
2017/01/31 by Manel Dahmene, Morgan Bérard, Abid Oueslati · 20 citations
Medicine · Neuroscience · #Parkinson's Disease Mechanisms and Treatments #Alzheimer's disease research and treatments #Genetic Neurodegenerative Diseases
paper · pdf · doi:10.1074/jbc.m116.759373
Abstract
substrate of this degradation pathway. In conclusion, our study provides a detailed description of the new degradation route of α-syn and offers new opportunities for the development of therapeutic strategies aiming to reduce α-syn protein accumulation and toxicity.
Citations
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