A Novel Gene Required for Rhamnose-Glucose Polysaccharide Synthesis inStreptococcus mutans

1999/10/15 by Yoshihisa Yamashita, Yukie Shibata, Yoshio Nakano +4 · 18 citations
Biochemistry, Genetics and Molecular Biology · Materials Science · #Glycosylation and Glycoproteins Research #Genomics and Phylogenetic Studies #Enzyme Structure and Function

paper · pdf · doi:10.1128/jb.181.20.6556-6559.1999

Abstract

Gene rgpG is required for biosynthesis of rhamnose-glucose polysaccharide (RGP) in Streptococcus mutans. Its deduced amino acid sequence had similarity to WecA, which initiates syntheses of enterobacterial common antigen and some O antigens in Escherichia coli. Gene rgpG complemented a wecA mutation of E. coli, suggesting that rgpG may function similarly in RGP synthesis.

Cited by

• Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen. [europepmc]
• The Biology of Streptococcus mutans . [europepmc]
• Discovery of an RmlC/D fusion protein in the microalga Prymnesium parvum and its implications for NDP-β-l-rhamnose biosynthesis in microalgae. [europepmc]
• Streptococcus mutans requires mature rhamnose-glucose polysaccharides for proper pathophysiology, morphogenesis and cellular division. [europepmc]
• Quantitative Proteomics Uncovers the Interaction between a Virulence Factor and Mutanobactin Synthetases in Streptococcus mutans . [europepmc]
• Disruption of l-Rhamnose Biosynthesis Results in Severe Growth Defects in Streptococcus mutans. [europepmc]
• LytR-CpsA-Psr Glycopolymer Transferases: Essential Bricks in Gram-Positive Bacterial Cell Wall Assembly. [europepmc]
• Modifications of cell wall polymers in Gram-positive bacteria by multi-component transmembrane glycosylation systems. [europepmc]
• Modification of cell wall polysaccharide guides cell division in Streptococcus mutans. [europepmc]
• Streptococcus mutans Lacking sufCDSUB Is Viable, but Displays Major Defects in Growth, Stress Tolerance Responses and Biofilm Formation. [europepmc]
• Cell wall polysaccharides of Gram positive ovococcoid bacteria and their role as bacteriophage receptors. [europepmc]
• Bipartite rgp Locus Diversity in Streptococcus thermophilus Corresponds to Backbone and Side Chain Differences of Its Rhamnose-Containing Cell Wall Polysaccharide. [europepmc]
• Impacts of a DUF2207 Family Protein on Streptococcus mutans Stress Tolerance Responses and Biofilm Formation. [europepmc]
• Anti-bacterial and anti-biofilm activities of arachidonic acid against the cariogenic bacterium Streptococcus mutans . [europepmc]
• Structure and mechanism of biosynthesis of Streptococcus mutans cell wall polysaccharide. [europepmc]
• Insights Into the Role of Streptococcus mutans and Candida albicans in Dental Biofilm Formation and Cariogenicity: A Literature Review. [europepmc]
• In Silico Identification of Dual-Action Compounds Targeting TLR2 and Streptococcus mutans Proteins for the Prevention of Early Childhood Caries. [europepmc]
• Characterization of RmlABCD Enzymes from Marine Bacteria and Efficient Synthesis of dTDP-L-Rhamnose. [europepmc]

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