High Rate of Intestinal Colonization with Extended-Spectrum-β-Lactamase-Producing Organisms in Household Contacts of Infected Community Patients

2008/06/19 by Aránzazu Valverde, Fabio Grill, Teresa M. Coque +4 · 1 citation
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Antibiotic Resistance in Bacteria #Antibiotic Use and Resistance #Vibrio bacteria research studies

paper · doi:10.1128/jcm.01008-08

openalex publication_date 2008/06/19 · openalex created_date 2016/06/24 · openalex updated_date 2026/05/21

Abstract

Fecal carriage of extended-spectrum-beta-lactamase (ESBL)-producing organisms was detected in 70% of index cases of patients (n = 40) with community-acquired infections due to ESBL producers and reached 16.7% in household contacts (n = 54). A total of 66% of ESBL-producing organisms from index cases were indistinguishable from isolates from household contacts by pulsed-field gel electrophoresis. Patients with community infections and members of their households represent a reservoir for ESBL producers, increasing dispersal of resistance in healthy people.

Citations

• Human intestinal bacteria as reservoirs for antibiotic resistance genes

Cited by

• Beta-lactamase [wikipedia]

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