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The Roots of Bioinformatics in Theoretical Biology

2011/03/31 by Paulien Hogeweg · 2 citations
Biochemistry, Genetics and Molecular Biology · #Evolution and Genetic Dynamics #Bioinformatics and Genomic Networks #Gene Regulatory Network Analysis

paper · pdf · doi:10.1371/journal.pcbi.1002021

openalex publication_date 2011/03/31 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22

Abstract

From the late 1980s onward, the term "bioinformatics" mostly has been used to refer to computational methods for comparative analysis of genome data. However, the term was originally more widely defined as the study of informatic processes in biotic systems. In this essay, I will trace this early history (from a personal point of view) and I will argue that the original meaning of the term is re-emerging.

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