Parallel Evolution of Bacillus thuringiensis Toxin Resistance in Lepidoptera

2011/08/13 by Simon W. Baxter, Francisco Rubén Badenes‐Pérez, Anna Morrison +6 · 3 citations
Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #Insect Resistance and Genetics #Genetically Modified Organisms Research #Insect Pest Control Strategies

paper · pdf · doi:10.1534/genetics.111.130971

openalex publication_date 2011/08/13 · openalex created_date 2016/06/24 · openalex updated_date 2026/08/04

Abstract

Despite the prominent and worldwide use of Bacillus thuringiensis (Bt) insecticidal toxins in agriculture, knowledge of the mechanism by which they kill pests remains incomplete. Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function.

Citations

• Identification of a Gene Associated with Bt Resistance in Heliothis virescens
• Bacillus thuringiensis and Its Pesticidal Crystal Proteins

Cited by

• The food and environmental safety of Bt crops
• The delinquent director : company law
• Widespread convergence in toxin resistance by predictable molecular evolution
• Bacillus thuringiensis [wikipedia]