Structure of proteins: packing of alpha-helices and pleated sheets.

1977/10/01 by C. Chothia, Michael Levitt, David Richardson · 3 citations
Biochemistry, Genetics and Molecular Biology · Materials Science · #Protein Structure and Dynamics #Enzyme Structure and Function #Glycosylation and Glycoproteins Research

paper · doi:10.1073/pnas.74.10.4130

openalex publication_date 1977/10/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/11

Abstract

Simple models are presented that describe the rules for almost all the packing that occurs between and among alpha-helices and pleated sheets. These packing rules, together with the primary and secondary structures, are the major determinants of the three-dimensional structure of proteins.

Citations

• The structure of proteins: Two hydrogen-bonded helical configurations of the polypeptide chain

Cited by

• Early bioinformatics: the birth of a discipline—a personal view
• The Whole Structure of the 13-Subunit Oxidized Cytochrome c Oxidase at 2.8 Å
• Alpha helix [wikipedia]