V(D)J Recombination and the Evolution of the Adaptive Immune System

2003/10/12 by Eleonora Market, F. Nina Papavasiliou · 3 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #DNA Repair Mechanisms #Cytomegalovirus and herpesvirus research #Escherichia coli research studies

paper · pdf · doi:10.1371/journal.pbio.0000016

openalex publication_date 2003/10/12 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31

Abstract

In order for the immune system to generate its vast numbers of receptors, B- and T-cell receptor genes are created by recombining preexisting gene segments. This well- coordinated set of reactions is explained.

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