2016/12/01 by Steven M. Opal · 1 citation
Biochemistry, Genetics and Molecular Biology · Environmental Science · #Antibiotic Resistance in Bacteria #Bacteriophages and microbial interactions #Bacterial Identification and Susceptibility Testing
paper · pdf · doi:10.1186/s13054-016-1549-1
openalex publication_date 2016/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29
The emergence of multi-drug resistant (MDR) microbial pathogens threatens the very foundation upon which standard antibacterial chemotherapy is based. We must consider non-antibiotic solutions to manage invasive bacterial infections. Transition from antibiotics to non-traditional treatments poses real clinical challenges that will not be easy to solve. Antibiotics will continue to reliably treat some infections (e.g., group A streptococci and Treponema pallidum) but will likely need adjuvant therapies or will need to be replaced for many bacterial infections in the future.