2017/11/27 by Neil A. Holmes, Rebecca Devine, Zhiwei Qin +3 · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · #Microbial Natural Products and Biosynthesis #Genomics and Phylogenetic Studies #RNA and protein synthesis mechanisms
paper · pdf · doi:10.1016/j.jbiotec.2017.11.011
openalex publication_date 2017/11/27 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/02
Here we report the complete genome of the new species Streptomyces formicae KY5 isolated from Tetraponera fungus growing ants. S. formicae was sequenced using the PacBio and 454 platforms to generate a single linear chromosome with terminal inverted repeats. Illumina MiSeq sequencing was used to correct base changes resulting from the high error rate associated with PacBio. The genome is 9.6 Mbps, has a GC content of 71.38% and contains 8162 protein coding sequences. Predictive analysis shows this strain encodes at least 45 gene clusters for the biosynthesis of secondary metabolites, including a type 2 polyketide synthase encoding cluster for the antibacterial formicamycins. Streptomyces formicae KY5 is a new, taxonomically distinct Streptomyces species and this complete genome sequence provides an important marker in the genus of Streptomyces.