2012/01/01 by A. Del Prete, Antonella Scalera, Maddalena Iadevaia +6 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Alternative medicine #Chronic liver disease #Clinical trial #Curcumin #Curcumin's Biomedical Applications #Disease #Drug-Induced Hepatotoxicity and Protection #Intensive care medicine #Internal medicine #Medicine #Pathology #Pharmacological Effects of Natural Compounds #Pharmacology #Traditional Chinese medicine #Traditional medicine
paper · pdf · doi:10.1155/2012/837939
openalex publication_date 2012/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/23
Complementary and alternative medicine soughts and encompasses a wide range of approaches; its use begun in ancient China at the time of Xia dynasty and in India during the Vedic period, but thanks to its long-lasting curative effect, easy availability, natural way of healing, and poor side-effects it is gaining importance throughout the world in clinical practice. We conducted a review describing the effects and the limits of using herbal products in chronic liver disease, focusing our attention on those most known, such as quercetin or curcumin. We tried to describe their pharmacokinetics, biological properties, and their beneficial effects (as antioxidant role) in metabolic, alcoholic, and viral hepatitis (considering that oxidative stress is the common pathway of chronic liver diseases of different etiology). The main limit of applicability of CAM comes from the lacking of randomized, placebo-controlled clinical trials giving a real proof of efficacy of those products, so that anecdotal success and personal experience are frequently the driving force for acceptance of CAM in the population.