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Disinfection spreads antimicrobial resistance

2021/01/28 by Ji Lu, Jianhua Guo · 1 citation
Medicine · Dentistry · #Healthcare and Environmental Waste Management #SARS-CoV-2 detection and testing #Dental Research and COVID-19

paper · doi:10.1126/science.abg4380

openalex publication_date 2021/01/28 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/23

Abstract

During the COVID-19 pandemic, the use of disinfectants, alcohol-based hand sanitizers, and antiseptic hand wash has surged. As a precaution, many authorities have also increased chlorine dosage in wastewater disinfection to achieve a free chlorine residual concentration greater than 6.5 mg/liter (1), despite evidence that a free chlorine residual of just above 0.5 mg/liter can completely inactivate human coronavirus (2). These chemicals can reach aquatic and terrestrial environments through direct discharge of wastewater into receiving waters. Disinfection protocols put in place to prevent COVID-19 should be limited to the minimum required to kill severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and weighed against their potential to increase antimicrobial resistance (AMR).

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