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Chemical synapses without synaptic vesicles: Purinergic neurotransmission through a CALHM1 channel-mitochondrial signaling complex

2018/05/08 by Roman A. Romanov, Robert S. Lasher, Brigit High +15 · 2 citations
Nursing · Neuroscience · #Biochemical Analysis and Sensing Techniques #Neuroscience and Neuropharmacology Research #Olfactory and Sensory Function Studies

paper · doi:10.1126/scisignal.aao1815

openalex publication_date 2018/05/08 · openalex created_date 2018/05/17 · openalex updated_date 2026/08/01

Abstract

upon opening of the nonselective CALHM1 channels. These findings reveal a distinctive organelle signature and functional organization for regulated, focal release of purinergic signals in the absence of synaptic vesicles.

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